Suppression of pyr-3 mutants by arg-12 mutants
نویسندگان
چکیده
منابع مشابه
An Enzymatic Difference among Pyr-3 Mutants of Neurospora Crassa.
The pyrimidine-3 mutants of Neurospora crassa have received considerable attention in the past. Mitchell and Mitchell' described experiments, using pyr-3a (37301), 3b (37815; temperature sensitive), and 3d (45502), which indicated that the pyr-3a and 3b mutations represent a genetic unit distinct from 3d. The evidence for this view was that pyrimidine-independent heterocaryons could be formed b...
متن کاملFrameshift suppression by thyA mutants of Escherichia coli K-12.
We have extended our previous study on the suppression of frameshift mutants by Escherichia coli thyA mutants by assaying suppression of 15 rIIB frameshift mutants of bacteriophage T4 on one of our suppressing thyA mutant strains. The majority of insertion mutants were suppressible, whereas none of the deletion mutants tested was suppressible. Frameshift suppression could be inhibited by adding...
متن کاملA mutation reducing feedback regulation by arginine in suppressed pyr-3 mutants in Neurospora.
D O U B L E mutants in Neurospora carrying a suppressible pyr-3 mutation and the suppressor, arg-12", will grow on unsupplemented medium, but unlike wild type, display a profound sensitivity to the normal metabolite, L-arginine. Asexual spores, or conidia, of such double mutants will not grow when placed on minimal agar medium supplemented with as little as 0.5 pg/ml arginine (DAVIS 1961). If t...
متن کاملloss of human tyrosinase dopa oxidase activity in artificial m374 arg and m 374 lys mutants
tyrosinase (ec: 1.14.18.1) is a copper - containing enzyme which is distributed in all domains of life such as prokaryote, eukaryote, mammals, invertebrates and plants. tyrosinase catalyzes the oxidation of monophenols to diphenols and diphenols to o-quinones . the tyrosinase crystallographic data shows two histidine -rich regions named cua and cub. a loop containing residues m374, s375 and v37...
متن کاملSuppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genes.
The alkB gene is one of a group of alkylation-inducible genes in Escherichia coli, and its product protects cells from SN2-type alkylating agents such as methyl methanesulfonate (MMS). However, the precise biochemical function of the AlkB protein remains unknown. Here, we describe the cloning, sequencing, and characterization of three Saccharomyces cerevisiae genes (YFW1, YFW12, and YFW16) that...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Fungal Genetics Reports
سال: 1965
ISSN: 1941-4765
DOI: 10.4148/1941-4765.2094